HPS-1 Monoclonal Antibody, 100ul Rotator KLF8 encodes Kruppel like factor

KLF8 encodes Kruppel like factor 8 which is a member of the Sp/KLF family of transcription factors

Some of the isoforms contain regions of similarity to beta-defensins| a family of antimicrobial peptides

|Serine/threonine kinase that may play a role in mediating the growth-factor and stress induced activation of the transcription factor CREB

Studies in mice showed that this gene was co-expressed with nuclear-encoded mitochondrial genes and the encoded protein specifically controlled endothelial uptake of fatty acids

In conjunction with complement component 1| q subcomponent| B chain (C1QB)| this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease

HPS-1 Monoclonal Antibody, 100ul Rotator KLF8 encodes Kruppel like factorThis gene encodes a protein that may play a role in organelle biogenesis associated with melanosomes, platelet dense granules, and lysosomes. The encoded protein is a component of three different protein complexes termed biogenesis of lysosome related organelles complex (BLOC) 3, BLOC4, and BLOC5. Mutations in this gene are associated with Hermansky Pudlak syndrome type 1. Alternative splicing results in multiple transcript variants. A pseudogene