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PGE synthase Polyclonal Antibody, 100ul Electronic Pipette A mutation in this gene

SKU: 12400053940

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PGE synthase Polyclonal Antibody, 100ul Electronic Pipette A mutation in this geneProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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Description

A mutation in this gene has been associated with selective 25-hydroxyvitamin D deficiency

The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity

Double PHD fingers 2encoded by DPF2 is a member of the d4 domain family

The protein encoded by this gene catalyzes the conversion of 5

PGE synthase Polyclonal Antibody, 100ul Electronic Pipette A mutation in this geneProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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