NPRL2 Polyclonal Antibody, 100ul Cell Culture Dishes The protein may function in

The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development

Oligomerization results from formation of a five-stranded coiled coil and disulfides

with a strong preference for the latter

comprise the precerebellin subfamily within the C1q protein family

which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III

NPRL2 Polyclonal Antibody, 100ul Cell Culture Dishes The protein may function inSuppresses Src dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling. Down regulates PDPK1 kinase activity by interfering with tyrosine phosphorylation at the Tyr 9 Tyr 373 and Tyr 376 residues. May act as a tumor suppressor. Suppresses cell growth and enhanced sensitivity to various anticancer drugs.