Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Polyglutamine repeat expansion in the

Polyglutamine repeat expansion in the AR is linked to Kennedy's disease (X-linked spinal and bulbar muscular atrophy)

This gene may also be involved in determining the polarity of photoreceptor cells in the retina

Genetic variation at this locus has been associated with a range of behavioral phenotypes

Localizes to centrosomes

including schizophrenia

Histone H2B (Mono Methyl Lys5) Polyclonal Antibody, 100ul Polyclonal Antibodies Polyglutamine repeat expansion in theHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.