Phospho-BRCA1 (S1524) Polyclonal Antibody, 100ul Gene Synthesis This protein is a receptor

This protein is a receptor for members of the epidermal growth factor family

May play a role as calcium-regulated intrinsic membrane protein

More than 80 different mutations in this gene have been reported

Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene| however| they were found to be nonsense-mediated mRNA decay (NMD) candidates| hence not represented

some seem to shuttle between the nucleus and the cytoplasm

Phospho-BRCA1 (S1524) Polyclonal Antibody, 100ul Gene Synthesis This protein is a receptorBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal