SP-100 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The yeast homolog

The yeast homolog

This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene

This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family

and CDK8 that can negatively regulate transactivation by mediator

Mediates the proteolytic cleavage of HP/haptoglobin in the endoplasmic reticulum

SP-100 Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The yeast homologSP100 (SP100 nuclear antigen) encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO 1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for SP100; one