AES Polyclonal Antibody, 100ul Mammalian Expression It is an activator of

It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo

The protein encoded by this gene is a member of the ADAM (a disintegrin and metalloproteinase) protein family

Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells

Reduced expression and rearrangement of this gene have been detected in various cancers

subcellular location:Upon binding to M-Ras

AES Polyclonal Antibody, 100ul Mammalian Expression It is an activator ofThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms