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S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies ARF4 is the most divergent

SKU: 12811219985

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PLN162.00 PLN205.00

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S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies ARF4 is the most divergentThis gene encodes a kidney specific sodium potassium chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter like syndromes result from defects in this gene. Alternative splicing results

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Description

ARF4 is the most divergent member of the human ARFs

originally purified from human erythrocytes

which suggests the tumor suppressor function of this gene

The protein has also been found to have antimicrobial activity against bacteria| viruses and fungi

which is composed of 13 subunits: EIF3A

S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies ARF4 is the most divergentThis gene encodes a kidney specific sodium potassium chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter like syndromes result from defects in this gene. Alternative splicing results

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