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SAM10 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays The other two isoforms| p52Shc

SKU: 12825681156

4.7
PLN97.20 PLN122.20

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SAM10 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays The other two isoforms| p52Shc

Store: avramcheva.com · Domain: avramcheva.com

Description

The other two isoforms| p52Shc and p46Shc| link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2/SOS complex

which result in multiple fusion proteins including EWS-ETV1 in Ewing sarcoma and at least 10 ETV1 partners (see PMID: 19657377

Has neurite extension activity

This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen

It localizes primarily within subnuclear foci associated with the nuclear matrix

SAM10 Rabbit Polyclonal Antibody, 20ul Cellular Function Assays The other two isoforms| p52Shc

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