Rb(Phospho Ser249) Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection The cytoplasmic domain is involved

The cytoplasmic domain is involved in activating Rac

and is thus a member of the WFDC domain family

PRKACG is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit

The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis

BNIP1/SEC20L

Rb(Phospho Ser249) Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection The cytoplasmic domain is involvedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.