CKR-5(Phospho Ser349) Polyclonal Antibody, 100ul Recombinant Protein Expression An autosomal recessive form of

An autosomal recessive form of juvenile amyotrophic lateral sclerosis was originally mapped to a region of chromosome 2 that includes ALS2CR11

This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus

and thus activating caspase-3 activation

The mRNA of this gene is subject to multiple RNA editing events

This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex

CKR-5(Phospho Ser349) Polyclonal Antibody, 100ul Recombinant Protein Expression An autosomal recessive form ofThis gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co receptor for macrophage tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with the HIV infection resistance. The ligands of this receptor include