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Phospho-Akt1 (S246) Polyclonal Antibody, 20ul Multiplex Immunoassays Leukocyte immunoglobulin-like receptor subfamily A

SKU: 12890800016

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Phospho-Akt1 (S246) Polyclonal Antibody, 20ul Multiplex Immunoassays Leukocyte immunoglobulin-like receptor subfamily AThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

Leukocyte immunoglobulin-like receptor subfamily A member 1 is predominantly expressed in B cells

Several splice variants encoding different isoforms have been found for this gene

It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane

COMT is important in the metabolism of catechol drugs used in the treatment of hypertension

Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites

Phospho-Akt1 (S246) Polyclonal Antibody, 20ul Multiplex Immunoassays Leukocyte immunoglobulin-like receptor subfamily AThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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