OTOGL Rabbit Polyclonal Antibody, 20ul Bottle-Top Dispenser subunit:Binds STX5A

subunit:Binds STX5A

with some of them functioning as activators and some as repressors of transcription

|The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion| thus inhibiting the enzyme

Three transcript variants encoding three different isoforms have been found for this gene

The product of this gene catalyzes the dehydrogenation of L-gulonate into dehydro-L-gulonate in the uronate cycle

OTOGL Rabbit Polyclonal Antibody, 20ul Bottle-Top Dispenser subunit:Binds STX5AThe protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness.