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CTND2 Polyclonal Antibody, 50ul Recombinant Protein Expression The activity of the protein

SKU: 12994009496

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CTND2 Polyclonal Antibody, 50ul Recombinant Protein Expression The activity of the proteinThis gene encodes an adhesive junction associated protein of the armadillo beta catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E

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Description

The activity of the protein is negatively regulated by its SH3 domain

resulting in its accumulation at intranuclear foci induced by DNA damage

TP and TP5 may play a role in T-cell development and function

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the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain

CTND2 Polyclonal Antibody, 50ul Recombinant Protein Expression The activity of the proteinThis gene encodes an adhesive junction associated protein of the armadillo beta catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E

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