IGF2 Polyclonal Antibody, 50ul Plasma Among its related pathways are

Among its related pathways are Translation Insulin regulation of translation and Wnt signaling pathway (KEGG)

Separately| it interacts with RhoA through a RhoGAP domain| and stimulates RhoA-dependent GTPase activity

Proteolytic processing is required to generate a mature subunit

This gene is expressed mainly in testis with weak expression in the brain

The serine protease subunits C1r and C1s form a Ca(2+)-dependent C1s-C1r-C1r-C1s tetramer

IGF2 Polyclonal Antibody, 50ul Plasma Among its related pathways areThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.