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DUS14 Polyclonal Antibody, 50ul Recombinant Protein Expression Mutations in this gene are

SKU: 13048170710

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DUS14 Polyclonal Antibody, 50ul Recombinant Protein Expression Mutations in this gene areDual specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine based protein tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C terminal catalytic domain but lacks the N terminal CH2 domain found in the MKP

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Description

Mutations in this gene are associated with neutrophil immunodeficiency syndrome

Mutations and deletions in this gene are associated with benign hereditary chorea| choreoathetosis| congenital hypothyroidism| and neonatal respiratory distress| and may be associated with thyroid cancer

Its main purpose is to provide materials for subsequent experiments such as cloning

upon ligand binding

The expression of AIFM2 is also found to be induced by tumor suppressor protein p53 in colon cancer cells

DUS14 Polyclonal Antibody, 50ul Recombinant Protein Expression Mutations in this gene areDual specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine based protein tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C terminal catalytic domain but lacks the N terminal CH2 domain found in the MKP

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