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SLP-76 Polyclonal Antibody, 50ul[BT-AP08367] Funnels and it has been proposed

SKU: 13062199381

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SLP-76 Polyclonal Antibody, 50ul[BT-AP08367] Funnels and it has been proposedSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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Description

and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway

Immune Repertoire refers to the set of all functionally diversified B cells and T cells in a person's circulatory system

U3 small nucleolar ribonucleoprotein) encodes the human homolog of the yeast Imp3 protein

Plays a role in the inhibition of T-cell proliferation via IL10 secretion by cutaneous dendritic cells

The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis

SLP-76 Polyclonal Antibody, 50ul[BT-AP08367] Funnels and it has been proposedSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic

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