p27(Phospho Ser178) Polyclonal Antibody, 50ul Proteases PRPF38A (Pre-mRNA-splicing factor 38A) is

PRPF38A (Pre-mRNA-splicing factor 38A) is a 312 amino acid nuclear protein that is likely required for pre-mRNA splicing

This gene is intronless and overlaps the 3' UTR of the WWC2 gene (GeneID: 80014) on the opposite strand

Detected at very low levels in brain

Mutations in this gene result in one form of autosomal dominant hearing impairment

RRAGC encodes a member of the GTR/RAG GTP-binding protein family

p27(Phospho Ser178) Polyclonal Antibody, 50ul Proteases PRPF38A (Pre-mRNA-splicing factor 38A) isThis gene encodes a cyclin dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A p21. The encoded protein binds to and prevents the activation of cyclin E CDK2 or cyclin D CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from