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PAR4 Polyclonal Antibody, 20ul[BT-AP12783] Pathway and Network Analysis GATA6 is a member of

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PAR4 Polyclonal Antibody, 20ul[BT-AP12783] Pathway and Network Analysis GATA6 is a member ofThe tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1 interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

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Description

GATA6 is a member of a small family of zinc finger transcription factors that play an important role in the regulation of cellular differentiation and organogenesis during vertebrate development

The 5' portion of this gene and two neighboring cytochrome p450 genes are included in a deletion that results in an autosomal-dominant form of nonsyndromic optic nerve aplasia (ONA)

This gene encodes a transmembrane protein that belongs to the Tmemb_18A family

and act as a negative regulator of human immunodeficiency virus type 1 (HIV-1) Tat protein

This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T-lymphocytes

PAR4 Polyclonal Antibody, 20ul[BT-AP12783] Pathway and Network Analysis GATA6 is a member ofThe tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1 interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

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