CALR3 Polyclonal Antibody, 50ul Vacuum Aspirator In humans deficiency of this

In humans deficiency of this protein is associated with increased risk of meningococcal infections

The encoded protein is a scaffolding protein that may influence the activity of at least one member of the cytohesin/ARNO family in response to specific cellular stimuli

There are pseudogenes for TFAM on chromosomes 6

The RefSeq contains this polymorphism

Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates

CALR3 Polyclonal Antibody, 50ul Vacuum Aspirator In humans deficiency of thisThe protein encoded by this gene belongs to the calreticulin family, members of which are calcium binding chaperones localized mainly in the endoplasmic reticulum. This protein is also localized to the endoplasmic reticulum lumen, however, its capacity for calcium binding may be absent or much lower than other family members. This gene is specifically expressed in the testis, and may be required for sperm fertility. Mutation in this gene has been