IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents Contains 10 EGF-like domains

Contains 10 EGF-like domains

This gene encodes a protein with similarity to members of the myosin light chain kinase family

This protein forms heterodimers with the gene product of the mutL homolog 1 (MLH1) gene to form the MutL-alpha heterodimer

tissue specificity:Expression is restricted to the hematopoietic tissues with the exception of liver

Mutations in this gene have been associated with X-linked mental retardation

IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents Contains 10 EGF-like domainsIGFBP7 encodes a member of the insulin like growth factor (IGF) binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF I and IGF II with relatively low affinity, and belongs to a subfamily of low affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants