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Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions NPR was determined to be

SKU: 1356873434

4.6
PLN97.20 PLN136.20

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Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions NPR was determined to beThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

NPR was determined to be a member of a distinct pentraxin protein subfamily

It plays a role in neuronal activity and a potential biological role in the regulation of N-methyl-D-aspartate (NMDA) receptor activity in these peripheral organs as well

PTM:Sumoylated

SERPINB5 is a Protein Coding gene

and the other variants encode the same protein

Rb(Phospho Thr826) Polyclonal Antibody, 20ul Buffer Solutions NPR was determined to beThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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