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MLK3(Phospho Ser674) Polyclonal Antibody, 100ul NGS Oligos SCN1A encodes a sodium channel

SKU: 13766225436

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MLK3(Phospho Ser674) Polyclonal Antibody, 100ul NGS Oligos SCN1A encodes a sodium channelThe protein encoded by this gene is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF kappaB mediated by Rho family

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Description

SCN1A encodes a sodium channel alpha subunit

Members of this subfamily are characterized by an extracellular V-set immunoglobulin-like domain followed by two C2-set immunoglobulin-like domains| and the cytoplasmic tyrosine-based motifs ITIM and SLAM-like

and in the 3' UTR of transferrin receptor mRNA

This protein is a member of the WD-repeat HIR1 family and may also be involved in DNA repair

but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited

MLK3(Phospho Ser674) Polyclonal Antibody, 100ul NGS Oligos SCN1A encodes a sodium channelThe protein encoded by this gene is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF kappaB mediated by Rho family

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