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p53 Monoclonal Antibody(6C4), 20ul Glassware Sets Cytochrome b5 type A encoded

SKU: 13846050987

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SEK97.20 SEK147.20

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p53 Monoclonal Antibody(6C4), 20ul Glassware Sets Cytochrome b5 type A encodedThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

Cytochrome b5 type A encoded by CYB5A is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin

This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs)

In mammalian cells the enzyme is composed of four different chains: alpha

High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation

Golgi reassembly-stacking protein 2 also plays a role in the intracellular transport of transforming growth factor alpha and may function as a molecular chaperone

p53 Monoclonal Antibody(6C4), 20ul Glassware Sets Cytochrome b5 type A encodedThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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