eIF5B Polyclonal Antibody, 50ul Roller Bottles moderately in brain and pituitary

moderately in brain and pituitary gland

Knockout mice lacking this gene exhibit abnormalities related to development and reproduction

Polymorphisms in this gene have been linked to breast and prostate cancer

It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions

and the suppression of tumorigenesis

eIF5B Polyclonal Antibody, 50ul Roller Bottles moderately in brain and pituitaryAccurate initiation of translation in eukaryotes is complex and requires many factors, some of which are composed of multiple subunits. The process is simpler in prokaryotes which have only three initiation factors (IF1, IF2, IF3). Two of these factors are conserved in eukaryotes: the homolog of IF1 is eIF1A and the homolog of IF2 is eIF5B (eukaryotic translation initiation factor 5B). The gene encodes eIF5B. Factors eIF1A and eIF5B interact on the