MYOZ2 Polyclonal Antibody, 20ul Glassware Class I molecules play a

Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen

Several transcript variants encoding different isoforms have been found for NCOA3

some of which are associated with Creutzfeldt-Jakob disease

metastasis

Alternative splicing of this gene results in two transcript variants encoding different isoforms

MYOZ2 Polyclonal Antibody, 20ul Glassware Class I molecules play aThe protein encoded by MYOZ2 (myozenin 2) belongs to a family of sarcomeric proteins that bind to calcineurin, a phosphatase involved in calcium dependent signal transduction in diverse cell types. These family members tether calcineurin to alpha actinin at the z line of the sarcomere of cardiac and skeletal muscle cells, and thus they are important for calcineurin signaling. Mutations in MYOZ2 cause cardiomyopathy familial hypertrophic type 16, a