LKB1 Polyclonal Antibody, 20ul[BT-AP05038] Sealing Film Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled amine receptor activity

Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers

A chromosomal translocation involving this gene and the IgH locus

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA

BPTI/Kunitz inhibitor and E2 domains in the middle region

LKB1 Polyclonal Antibody, 20ul[BT-AP05038] Sealing Film Gene Ontology (GO) annotations relatedSTK11 (serine threonine kinase 11), which encodes a member of the serine threonine kinase family, regulates cell polarity and functions as a tumor suppressor. Mutations in STK11 have been associated with Peutz Jeghers syndrome, an autosomal dominant disorder characterized by the growth of polyps in the gastrointestinal tract, pigmented macules on the skin and mouth, and other neoplasms. Alternate transcriptional splice variants of STK11 have been