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PEK/PERK Polyclonal Antibody, 50ul Miscellaneous EDC4 and DDX6

SKU: 14059255288

4.4
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PEK/PERK Polyclonal Antibody, 50ul Miscellaneous EDC4 and DDX6The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in

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Description

EDC4 and DDX6

mOrange and mOrange2 are extremely bright orange fluorescent protein monomers which can be used as tags or reporters

This protein forms a trimeric complex with cyclin H and MAT2

This protein interacts directly with SMN

Several alternatively spliced transcript variants encoding different isoforms have been described

PEK/PERK Polyclonal Antibody, 50ul Miscellaneous EDC4 and DDX6The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in

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