TBK1/NAK(Phospho-Ser172) Rabbit Polyclonal Antibody, 20ul Cryogenic Vials May mediate brain damage by

May mediate brain damage by nucleotides and CysLTs following ischemia

It is uncertain whether Met-1 or Met-25 is the initiator

This enzyme plays a central role in the generation of purine nucleotides through the purine salvage pathway

and is also highly expressed in skeletal and heart muscles

A unique "two-hybrid" system has been developed using GAL4 fusions in yeast to identify specific protein-protein interactions

TBK1/NAK(Phospho-Ser172) Rabbit Polyclonal Antibody, 20ul Cryogenic Vials May mediate brain damage byThe NF kappa B (NFKB) complex of proteins is inhibited by I kappa B (IKB) proteins which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain