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This gene has also been shown to be rearranged in certain cancer cells

Through its ability to signal initiation of the last step of vertebrate cytokinesis

brain and placenta

The encoded protein may protect cells from programmed cell death

TOK-1 Polyclonal Antibody, 50ul Culture Tubes Experience the power of LightNing™BCCIP (BRCA2 and CDKN1A interacting protein) product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N terminal half shares moderate homology with regions of calmodulin and M calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a