NFκB-p105(Phospho Ser927) Polyclonal Antibody, 100ul Purification Defects in HCCS are a

Defects in HCCS are a cause of microphthalmia syndromic type 7 (MCOPS7)

This polymorphism is also associated with the occurrence of the splice variant GNB3-s

and appears to bind collagen in this form

The protein encoded belongs to the collectin family and is an important element in the innate immune system

This gene may have arose from a gene duplication event and its gene duplicate is also present on chromosome 1

NFκB-p105(Phospho Ser927) Polyclonal Antibody, 100ul Purification Defects in HCCS are aThis gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF kappa B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra and extra cellular stimuli such as cytokines oxidant free radicals ultraviolet irradiation and