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FoxO3A Polyclonal Antibody, 100ul[BT-AP03333] Electrophoresis & Labeling This gene contains a region

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FoxO3A Polyclonal Antibody, 100ul[BT-AP03333] Electrophoresis & Labeling This gene contains a regionFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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Description

This gene contains a region in the coding sequence which has a variable number (>100) of 48 nt tandem repeats

Sialic acid-binding paired receptor which may activate associated receptors

The encoded protein is a serine/threonine protein kinase

TXNRD2 encodes a member of the class I pyridine nucleotide-disulfide oxidoreductase family

It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors

FoxO3A Polyclonal Antibody, 100ul[BT-AP03333] Electrophoresis & Labeling This gene contains a regionFOXO3 belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. FOXO3 likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.

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