Human Dickkopf-related Protein 4, DKK4 ELISA Kit, 96T Recombinant Ab Production The BCL7A protein is encoded

The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line

May play a role in haemostasis and thrombosis owing to its ability to bind fibrinogen and incorporate into clots

Mutations in this gene have been associated with Orofaciodigital Syndrome IV and Joubert Syndrom 18

This gene encodes a ubiquitin specific processing protease that was first identified as a substrate of the VHL (von Hippel-Lindau disease) protein E3 ubiquitin ligase complex

The encoded protein is insulin-responsive

Human Dickkopf-related Protein 4, DKK4 ELISA Kit, 96T Recombinant Ab Production The BCL7A protein is encodedAntagonizes canonical Wnt signaling by inhibiting LRP5 6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5 6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone