GRK2(Phospho-Tyr86) Polyclonal Antibody, 20ul Palm Micro Centrifuges Mutations in this gene are

Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia

also known as HP43

including cell adhesion proteins

Expression of this gene is up-regulated in some types of cancer

and expression of this gene is altered in some types of cancer

GRK2(Phospho-Tyr86) Polyclonal Antibody, 20ul Palm Micro Centrifuges Mutations in this gene areThe product of this gene phosphorylates the beta 2 adrenergic receptor and appears to mediate agonist specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta adrenergic and related G protein coupled receptors. Abnormal coupling of beta adrenergic receptor to G protein is involved in the pathogenesis of the failing heart.