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ZnT-8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Interleukin-20 receptor subunit alpha is

SKU: 14411760892

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ZnT-8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Interleukin-20 receptor subunit alpha isZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent

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Description

Interleukin-20 receptor subunit alpha is a subunit of the receptor for interleukin 20

Torsin-1A-interacting protein 1 localizes to the inner nuclear membrane and may be involved in maintaining the attachment of the nuclear membrane to the nuclear lamina during cell division

CD3d molecule encoded by CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction

There is a single exon pseudogene mapped on chromosome X

tissue specificity:Ubiquitously expressed in all tissues examined with high levels in the testis

ZnT-8 Polyclonal Antibody, 50ul Immune Repertoire Sequencing Interleukin-20 receptor subunit alpha isZinc transporter 8 encoded by SLC30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles. SLC30A8 is expressed at a high level only in the pancreas, particularly in islets of Langerhans. The encoded protein colocalizes with insulin in the secretory pathway granules of the insulin secreting INS 1 cells. Allelic variants of this gene exist that confer susceptibility to diabetes mellitus, noninsulin dependent

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