FBX10 Rabbit Polyclonal Antibody, 100ul Cell Dissociation Binds preferrentially ferritin light chain

Binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1)

An important paralog of this gene is AATK

A pseudogene of PIK3CA has been defined on chromosome 22

Cut like homeobox 1 encoded by CUX1 is a member of the homeodomain family of DNA binding proteins

The protein contains multiple tetratricopeptide repeats that are required for optimal recognition of substrates

FBX10 Rabbit Polyclonal Antibody, 100ul Cell Dissociation Binds preferrentially ferritin light chainMembers of the F box protein family such as FBXO10 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004