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API5 Polyclonal Antibody, 50ul Gene Synthesis which is predicted to span

SKU: 14451815023

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API5 Polyclonal Antibody, 50ul Gene Synthesis which is predicted to spanAPI5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein (apoptosis inhibitor 5) suppresses the transcription factor E2F1 induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants

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Description

which is predicted to span the membrane four times

Isoform 1 C-terminal region is tyrosine-rich

This gene encodes a member of the desmoglein subgroup of desmosomal cadherins

a type I keratin

Involved in JUN ubiquitination and degradation

API5 Polyclonal Antibody, 50ul Gene Synthesis which is predicted to spanAPI5 encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein (apoptosis inhibitor 5) suppresses the transcription factor E2F1 induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants

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