RGPA1 Polyclonal Antibody, 20ul Serum & Sample Tubes Defects in this gene are

Defects in this gene are a cause of non-insulin-dependent diabetes mellitus (NIDDM)

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors

are nucleic acid-binding

WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD)| which may facilitate formation of heterotrimeric or multiprotein complexes

and filiform papilla

RGPA1 Polyclonal Antibody, 20ul Serum & Sample Tubes Defects in this gene areThis gene encodes a major subunit of the RAL GTPase activating protein. A similar protein in mouse binds E12, a transcriptional regulator of immunoglobulin genes. The mouse protein also functions in skeletal muscle by binding to the regulatory 14 3 3 proteins upon stimulation with insulin or muscle contraction. A pseudogene of this gene has been identified on chromosome 9.