CHERP Polyclonal Antibody, 50ul DNA Synthesis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been described for PXN

Contains 1 WWE domain

This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol

A read-through transcript composed of SPECC1L (sperm antigen with calponin homology and coiled-coil domains 1-like) and the downstream ADORA2A (adenosine A2a receptor) gene sequence has been identified| but it is thought to be non-coding

The encoded protein is an actin-binding protein that is activated by the serine/threonine kinase Akt and plays a role in cytoskeleton remodeling and cell migration

CHERP Polyclonal Antibody, 50ul DNA Synthesis Alternatively spliced transcript variants encodingInvolved in calcium homeostasis, growth and proliferation.,sequence Translation N terminally shortened.,Contains 1 CID domain.,Contains 1 G patch domain.,Contains 1 SURP motif repeat.,subcellular location: Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1.,tissue specificity: Expressed in brain, placenta, lung, liver, kidney, pancreas,