Bovine Myeloid Differentiation Primary Response Protein Myd88, MYD88 ELISA Kit , 96T Bacterial Expression Gene Ontology (GO) annotations related

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and G-protein coupled amine receptor activity

which is located on the X chromosome

Mutations that alter the jagged 1 protein cause Alagille syndrome

Mutations in this gene result in Bernard-Soulier syndromes and platelet-type von Willebrand disease

and the regulation of cell growth

Bovine Myeloid Differentiation Primary Response Protein Myd88, MYD88 ELISA Kit , 96T Bacterial Expression Gene Ontology (GO) annotations relatedAdapter protein involved in the Toll like receptor and IL 1 receptor signaling pathway in the innate immune response. Acts via IRAK1, IRAK2 and TRAF6, leading to NF kappa B activation, cytokine secretion and the inflammatory response. Increases IL 8 transcription. Involved in IL 18 mediated signaling pathway. Activates IRF1 resulting in its rapid migration into the nucleus to mediate an efficient induction of IFN beta, NOS2 INOS, and IL12A genes