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PKD2 Polyclonal Antibody, 100ul[BT-AP07231] Transporters Required for poly-ubiquitination and proteasome-mediated

SKU: 14753547072

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PKD2 Polyclonal Antibody, 100ul[BT-AP07231] Transporters Required for poly-ubiquitination and proteasome-mediatedThe protein kinase D2 encoded by PRKD2 belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants

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Description

Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle

NBPF5 contains one NBPF domain and is encoded by a gene that maps to human chromosome 1p13

The core complex possesses DNA-dependent ATPase activity

cancer-related encoded by NTPCR is a non-specific nucleoside triphosphatase that is slow-acting in vitro

a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade

PKD2 Polyclonal Antibody, 100ul[BT-AP07231] Transporters Required for poly-ubiquitination and proteasome-mediatedThe protein kinase D2 encoded by PRKD2 belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants

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