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CD6 Polyclonal Antibody, 50ul[BT-AP01538] Enzymes Alternatively spliced transcript variants encoding

SKU: 1507198864

4.3
SEK162.00 SEK203.00

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CD6 Polyclonal Antibody, 50ul[BT-AP01538] Enzymes Alternatively spliced transcript variants encodingCD5 has been identified as a transmembrane glycoprotein that is expressed on 70% of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper responsive to TCR mediated activation. CD5 associates with the TCR CD3 chain, and with the Src family kinase, Lck p56. The

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Description

Alternatively spliced transcript variants encoding different isoforms have been found for PSMD12

which are typical of the ADAMTS family

May be involved in fasciculation as well as myelination of developing neural axons

The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin

where it activates Ras

CD6 Polyclonal Antibody, 50ul[BT-AP01538] Enzymes Alternatively spliced transcript variants encodingCD5 has been identified as a transmembrane glycoprotein that is expressed on 70% of normal peripheral blood lymphocytes and on virtually all T lymphocytes in thymus and peripheral blood. Activation of T cells through the T cell receptor (TCR) results in tyrosine phosphorylation of CD5, and the absence of CD5 renders T cells hyper responsive to TCR mediated activation. CD5 associates with the TCR CD3 chain, and with the Src family kinase, Lck p56. The

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