S10AE Polyclonal Antibody, 20ul Biochemical Reagents This gene is a MAGE-B

This gene is a MAGE-B subfamily member of the MAGE gene family

a proteoglycan found in the extracellular matrix and most cells which is involved in cell migration and differentiation

Hsp27 is involved with cell growth and differentiation

Substrates of this enzyme include the tumor suppressor protein p53 and peroxisomal biogenesis factor 5 (PEX5)

It is primarily an alpha-helical protein with very little coiled coil| and binds directly to the largest subunit (p150) of dynactin

S10AE Polyclonal Antibody, 20ul Biochemical Reagents This gene is a MAGE-BThis gene encodes a member of the S100 protein family which contains an EF hand motif and binds calcium. The gene is located in a cluster of S100 genes on chromosome 1. Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863, 19351828).