MIB2 Polyclonal Antibody, 100ul Modification Enzymes The IGHM gene encodes the

The IGHM gene encodes the C region of the mu heavy chain| which d

encoded by separate genes

Participates in Wnt signaling (By similarity)

CAP-Gly domain containing linker protein 2 encoded by CLIP2 belongs to the family of cytoplasmic linker proteins

and they have a greater tendency to allow potassium to flow into the cell rather than out of it

MIB2 Polyclonal Antibody, 100ul Modification Enzymes The IGHM gene encodes theE3 ubiquitin protein ligase that mediates ubiquitination of Delta receptors, which act as ligands of Notch proteins. Positively regulates the Delta mediated Notch signaling by ubiquitinating the intracellular domain of Delta, leading to endocytosis of Delta receptors.,induction: Down regulated in many primary skin melanomas. Treatment with a demethylating agent, 5' aza 2 deoxycytidine, restores expression, suggesting that down regulation is the result