CL18A Rabbit Polyclonal Antibody, 20ul Drying & Desiccation Angelman and Prader-Willi syndromes are

Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and inner-membrane mitochondrial forms

These proteins are basic helix-loop-helix transcription factors which can act as tumor suppressors but lack DNA binding activity

calcium-mobilizing protein (VACM-1)

Replication factor C

CL18A Rabbit Polyclonal Antibody, 20ul Drying & Desiccation Angelman and Prader-Willi syndromes areThis is one of three closely related paralogous genes on chromosome 16 encoding secreted proteins containing C type lectin domains. These domains bind to carbohydrates in the presence of calcium and may be involved in cell adhesion immune response and apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.