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Paxillin Polyclonal Antibody, 100ul[BT-AP06953] Filtration PTK2 encodes a cytoplasmic protein

SKU: 15917615376

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DKK123.75 DKK149.75

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Paxillin Polyclonal Antibody, 100ul[BT-AP06953] Filtration PTK2 encodes a cytoplasmic proteinPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

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Description

PTK2 encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents

Mutations in SDCCAG8 are associated with retinal-renal ciliopathy

Mutations in this gene are associated with short stature

The protein encoded by this gene is a member of the mitogen-activated protein kinase (MAPK) family

It belongs to family 1 of the G protein-coupled receptors

Paxillin Polyclonal Antibody, 100ul[BT-AP06953] Filtration PTK2 encodes a cytoplasmic proteinPXN encodes a cytoskeletal protein involved in actin membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for PXN. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties.

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