IGF-IR Polyclonal Antibody, 100ul[BT-AP04399] Tubes The encoded protein is synthesized

The encoded protein is synthesized as a precursor protein and is proteolytically cleaved to form a secreted mature peptide

It phosporylates other proteins

Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome

GPBAR1 encodes a member of the G protein-coupled receptor (GPCR) superfamily

protein synthesis

IGF-IR Polyclonal Antibody, 100ul[BT-AP04399] Tubes The encoded protein is synthesizedIGF1R, this receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms