USP16 Polyclonal Antibody, 100ul Serological Pipets Involved in suppression of IL13-induced

Involved in suppression of IL13-induced STAT6 phosphorylation

The core complex possesses DNA-dependent ATPase activity

a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1)

There are two isoforms of this protein

and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression

USP16 Polyclonal Antibody, 100ul Serological Pipets Involved in suppression of IL13-inducedUSP16 encodes a deubiquitinating enzyme that is phosphorylated at the onset of mitosis and then dephosphorylated at the metaphase anaphase transition. It can deubiquitinate H2A, one of two major ubiquitinated proteins of chromatin, in vitro and a mutant form of the protein was shown to block cell division. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.