Parkin Polyclonal Antibody, 50ul Endonucleases & Exonucleases and at low levels in

and at low levels in placenta

Gene Ontology (GO) annotations related to this gene include chromatin binding and RNA polymerase II transcription corepressor activity

and induces apoptosis in transfected cells

It is overexpressed in Hodgkin's disease tissue and might participate in the interaction between the H&RS cells with their surrounding cells and might thus play a role in the pathogenesis of this disease and/or its associated immunodeficiency

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Parkin Polyclonal Antibody, 50ul Endonucleases & Exonucleases and at low levels inThe precise function of PARK2 is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation. Mutations in PARK2 are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease. Alternative splicing of PARK2 produces multiple transcript variants encoding distinct isoforms. Additional splice variants of PARK2 have