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Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 50ul Insect Expression 59 kDa and 66 kDa

SKU: 16489921825

4.7
PLN162.00 PLN184.00

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Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 50ul Insect Expression 59 kDa and 66 kDaThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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Description

59 kDa and 66 kDa

this interaction inhibits the binding of active AP1 to its target DNA

The genes encoding these microtubule constituents belong to the tubulin superfamily| which is composed of six distinct families

May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments

depending on whether it is bound to GTP or GDP

Shc(Phospho-Ser239/240) Rabbit Polyclonal Antibody, 50ul Insect Expression 59 kDa and 66 kDaThis gene encodes three main isoforms that differ in activities and subcellular location. While all three are adapter proteins in signal transduction pathways the longest (p66Shc) may be involved in regulating life span and the effects of reactive oxygen species. The other two isoforms p52Shc and p46Shc link activated receptor tyrosine kinases to the Ras pathway by recruitment of the GRB2 SOS complex. p66Shc is not involved in Ras activation. Unlike

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